ARA-290 is a non-erythropoietic peptide derived from erythropoietin, designed to reduce inflammation and promote nerve repair without the serious side effects typically associated with erythropoietin. At Direct Peptides, this innovative compound is highlighted for its potential therapeutic benefits.

What Is ARA-290?

ARA-290 is a small peptide fragment from erythropoietin, a protein critical for red blood cell production. Unlike erythropoietin itself, ARA-290 does not affect red blood cell levels. Instead, it targets the innate repair receptor (IRR) to encourage tissue repair and reduce inflammation.

Research suggests it may hold promise for treating autoimmune diseases, chronic pain, and diabetic neuropathy by reducing nerve inflammation and supporting healing processes.

Mechanism of Action

ARA-290 activates the innate repair receptor, a unique complex formed by the beta common receptor and the erythropoietin receptor on specific cells. This activation sparks protective pathways that dampen inflammation and encourage tissue regeneration. If you’re interested in exploring this promising therapy further, you
can Buy ARA-290 Peptide Saudia Arabia from trusted suppliers to tap into its regenerative potential.

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Structure of ARA-290

Sequence: H-Pyr-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser-OH
Molecular Formula: C51H84N16O21
Molecular Weight: 1257.3 g/mol
PubChem CID: 91810664

Research Benefits of ARA-290

Neuropathic Symptom Relief: Saudi Arabian studies show ARA-290 reduces neuropathic symptoms in type 2 diabetes and sarcoidosis patients. It can be administered intravenously or subcutaneously, offering flexible treatment options.
Metabolic Control: Beyond neuropathic relief, it shows promising effects on metabolic regulation in type 2 diabetes, making it valuable for managing complex conditions.
Corneal Nerve Fiber Density: Research indicates ARA-290 increases corneal nerve fiber density in patients with small nerve fiber loss due to sarcoidosis, highlighting its regenerative potential.
Chronic Neuropathic Pain: Acting via the IRR receptor complex, it alleviates chronic neuropathic pain in sarcoidosis patients.
SPECT Tracer Potential: It has been evaluated as a diagnostic tracer for cardiac ischemia, showing potential benefits in imaging ischemic regions.
Diabetic Neuropathy Treatment: Clinical trials confirm its safety and effectiveness in managing painful diabetic neuropathy, though larger studies are needed.
Neuroprotection: ARA-290 may protect nerve tissue and aid in conditions like post-stroke depression.
Apoptosis and Inflammation Reduction: It shows promise in reducing cell death and inflammation in vascular diseases such as critical limb ischemia.
Immune System Modulation: Studies suggest it modulates immune responses by targeting pathways that reduce inflammatory cytokines like IL-6 and improve antigen presentation, potentially benefiting transplantation outcomes.

Purchase ARA-290 for Research

Buy ARA-290 peptide vial 2 mg in Saudi Arabia, available as a lyophilized powder for laboratory research. This synthetic erythropoietin analogue activates the innate repair receptor without affecting red blood cell production. Available through Direct Peptides, it is an essential tool for inflammation and tissue repair studies.

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ARA-290 Nasal Spray

ARA-290 nasal spray in Saudi Arabia is offered in 15 ml and 30 ml bottles. The smaller size suits short-term trials, while the larger is more economical for extended research. Both provide the same high-quality formula in an easy-to-use spray, supporting flexible study designs.